Download E-books LC/MS Applications in Drug Development PDF

By Mike S. Lee

Breakthroughs in combinatorial chemistry and molecular biology, in addition to an total pattern towards sped up improvement, suggest the speed of pattern new release now a ways exceeds the speed of pattern research within the pursuit of manufacturing new and higher prescription drugs. LC/MS is an analytical device that is helping the researcher determine the main promising pattern early within the choice procedure, successfully making a shortcut to discovering new medicines. This booklet is the 1st to explain LC/MS purposes in the context of drug improvement, together with the invention, preclinical, scientific, and production phases.
as well as the thorough technical research of this software, LC/MS functions in Drug Development presents standpoint at the major alterations in concepts for pharmaceutical research. A technique evaluate of drug improvement from an analytical standpoint is equipped in addition to crucial info required to effectively carry a drug to industry. The incorporation of LC/MS is illustrated from aim to product. Chapters touching on the invention technique itself comprise:

  • Proteomics
  • Glycoprotein Mapping
  • Natural items Dereplication
  • Lead id Screening
  • Open-Access LC/MS
  • In Vitro Drug Screening

Written for either the analytical chemist who makes use of LC/MS purposes and the pharmaceutical scientist who works with the medicine they produce, LC/MS functions in Drug Development is the most desirable reference at the subject.

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